Blood Coagulation Activity of Purine Derivatives
نویسندگان
چکیده
منابع مشابه
Synthesis and Antithyroid Activity of Some 8-Substituted Purine Derivatives
Some novel as well as known derivatives of 8-sulfanyl-3,9dihydro-1H-purine-2,6-dione were synthesized and their antithyroid activity was measured in rats after administration of a daily dose of 20mg/kg via i.p. injection for 15 days. Free thyroxine and triiodothyronine concentrations were determined using radioimmunoassay technique. The assay results showed decrease in the hormonal concentratio...
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1. Factor VII, essentially free of Factor X but containing traces of prothrombin, and Factor X, very low in Factor VII, have been prepared by a combination of adsorption to and elution from barium sulfate and chromatography on diethylaminoethyl cellulose. 2. The activation of Factor X by lung microsomes is due to contamination of Factor X with Factor VII rather than to a direct attack on the Fa...
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In earlier papers the presence of protein decomposition products in soils was reported and it was shown that in soils the changes occurring in the decay of such plant and animal materials as get into the soil are similar to the changes occuring under other conditions in the laboratory or in nature. The presence of arginine and histidine in soils was definitely established by isolating these deg...
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The synthesis of a series of purine analogues of the acyclonucleoside compound 14 (acyclovir) is described. Compounds in this series have been shown to have pronounced activity against herpes virus-type l(HSV-1). The anti-viral activities of other analogs whose syntheses were recently reported [1] by us are also described
متن کاملBlood Coagulation
INTRODUCTION This section covers the means, as far as we now know them, by which components of the blood plasma produce an insoluble protein meshwork, or gel, at a site of blood-vessel damage. The plasma is normally completely fluid, containing all its proteins in soluble form. When the clotting system is activated at a site of blood-vessel damage, a series of proteolytic reactions is set going...
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ژورنال
عنوان ژورنال: The Journal of Kansai Medical University
سال: 1958
ISSN: 0022-8400
DOI: 10.5361/jkmu1956.10.4_29